SCHEMBL11565666

SCHEMBL11565666

CCCCCCCCN1C(=O)C(C)(C)NCC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
PTGS1 P23219 3/20 0.36
PTGS2 P35354 3/20 0.36
MGLL Q99685 3/20 0.36
FAAH O00519 3/20 0.36
CNR1 P21554 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
PRKCD Q05655 4/20 0.33
GBA1 P04062 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11095003 0.86 POLB (0.31)
SCHEMBL11562863 0.81 ALOX5 (0.35) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL11416938 0.79 MGLL (0.37) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL26289862 0.78 ALOX5 (0.39) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL11822945 0.75 PTGS1 (0.39) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL11849819 0.75 PTGS1 (0.39) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL26289325 0.68 MGLL (0.38) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL9578281 0.68 GBA1 (0.38) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL11165200 0.68 ALOX5 (0.36) ALOX5PTGS1PTGS2MGLLFAAH
SCHEMBL6550307 0.67 MGLL (0.50) ALOX5PTGS1PTGS2MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001284-A1 UV-light stabilized compositions containing substituted 2-keto-1,4-diazacycloalkanes The B.F. GOODRICH Company (US) 1979-04-04 EP disclosed