Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650756 | 0.77 | TSHR (0.44) | TSHRLMNAALDH1A1MAPTDPP4 | |
| SCHEMBL3955535 | 0.76 | CYP2D6 (0.42) | TSHRCYP2D6KMT2ASRCLMNA | |
| SCHEMBL858 | 0.76 | CYP2D6 (0.42) | TSHRCYP2D6KMT2ASRCLMNA | |
| Hydrochloric Acid SCHEMBL10708013 | 0.74 | HTT (0.44) | TSHRCYP2D6KMT2ALMNAMAPK1 | |
| SCHEMBL5517002 | 0.74 | CYP2D6 (0.41) | TSHRCYP2D6KMT2ASRCLMNA | |
| SCHEMBL4386400 | 0.73 | KMT2A (0.42) | TSHRCYP2D6KMT2ASRCLMNA | |
| SCHEMBL959684 | 0.73 | DPP4 (0.44) | CYP2D6KMT2ADPP4GLSF2 | |
| SCHEMBL7052526 | 0.73 | CYP2D6 (0.39) | TSHRCYP2D6KMT2ASRCLMNA | |
| SCHEMBL12555585 | 0.73 | CYP2D6 (0.44) | TSHRCYP2D6KMT2ASRCLMNA | |
| SCHEMBL96936 | 0.73 | HCAR2 (0.47) | CYP2D6KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153006-B1 | BENZOTRICYCLIC NITROGEN-CONTAINING DIONES AND A PROCESS FOR THE PRODUCTION THEREOF | WARNER-LAMBERT COMPANY (US) | 1988-07-06 | — | — | EP | claimed |
| EP-0153006-A1 | Benzotricyclic nitrogen-containing diones and a process for the production thereof | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | claimed |
| US-4530929-A | Tricyclic containing an imide group | WARNER-LAMBERT COMPANY (US) | 1985-07-23 | — | — | US | claimed |
| JP-58008005-A | — | — | None | — | — | JP | disclosed |
| CN-112778398-A | Liver-targeting drug, pharmaceutical composition thereof and application thereof | 杜心赟 | 2021-05-11 | — | — | CN | disclosed |
| CN-106255681-B | The method for being used to prepare substituted seromycin | 先正达参股股份有限公司 | 2019-11-22 | — | — | CN | disclosed |
| US-10308605-B2 | Proton pump inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-06-04 | — | — | US | disclosed |
| CN-109574825-A | A kind of synthetic method of phenylacetic acid | 江南大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-108822053-A | The method for being used to prepare substituted seromycin | 先正达参股股份有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-102712825-B | Coating agent and coated article | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2016-03-16 | — | — | CN | disclosed |
| EP-1696898-B1 | ZN 2+ -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | UNIV OHIO STATE RES FOUND (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2003099787-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-04 | — | — | WO | disclosed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-6284914-B1 | HYDROXAMIC ACID DERIVATIVES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-09-04 | — | — | US | disclosed |
| US-6147114-A | HYDROXAMIC ACID DERIVATIVES FROM TUMOR NECROSIS FACTOR CONVERTING ENZYME | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-11-14 | — | — | US | disclosed |
| CN-1041730-C | Process for preparing hydrogenated pyridine derivatives | SANKYO CO (JP) | 1999-01-20 | — | — | CN | disclosed |
| EP-0832875-A1 | HIGHLY WATER-SOLUBLE METALLOPROTEINASE INHIBITOR | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1998-04-01 | — | — | EP | disclosed |
| CN-1074446-A | Hydroxypyridine Derivatives | SANKYO CO (JP) | 1993-07-21 | — | — | CN | disclosed |
| CN-85103264-A | 9a-azepine-9a-homoerythromycin derivative | — | 1987-01-14 | — | — | CN | disclosed |
| JP-S588005-A | REPELLENT FOR NOXIOUS INSECT | EARTH CHEM CORP LTD | 1983-01-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308605-B2 | Proton pump inhibitors | HRH2, HRH4, HRH1 | TSHR 171/4885CYP2D6 112/4885KMT2A 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.