Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096818 | 0.88 | ACP3 (0.40) | KMT2AMAPK1ALDH1A1 | |
| SCHEMBL858 | 0.76 | CYP2D6 (0.42) | CYP2D6KMT2ASRCLMNAMAPK1 | |
| SCHEMBL3955535 | 0.76 | CYP2D6 (0.42) | CYP2D6KMT2ASRCLMNADPP4 | |
| SCHEMBL5517002 | 0.74 | CYP2D6 (0.41) | CYP2D6KMT2ASRCLMNADPP4 | |
| Hydrochloric Acid SCHEMBL10708013 | 0.74 | HTT (0.44) | CYP2D6KMT2ALMNAMAPK1TSHR | |
| SCHEMBL1156574 | 0.73 | TSHR (0.44) | CYP2D6KMT2ASRCLMNADPP4 | |
| SCHEMBL12555585 | 0.73 | CYP2D6 (0.44) | CYP2D6KMT2ASRCLMNAMAPK1 | |
| SCHEMBL4386400 | 0.73 | KMT2A (0.42) | CYP2D6KMT2ASRCLMNADPP4 | |
| SCHEMBL959684 | 0.73 | DPP4 (0.44) | CYP2D6KMT2ADPP4GLSF2 | |
| SCHEMBL96936 | 0.73 | HCAR2 (0.47) | CYP2D6KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891059-A | Electromagnetic radiation synthesis method and device of high-density molecular array chip | 深圳市华云智能健康有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-110546154-B | Fluorogenic substrates for glycosidases and related detection methods | 里昂师范大学 | 2024-04-05 | — | — | CN | disclosed |
| EP-3555112-B1 | FLUOROGENIC GLYCOSIDASE SUBSTRATE AND ASSOCIATED DETECTION METHOD | ECOLE NORMALE SUPERIEURE LYON (FR) | 2023-12-06 | — | — | EP | disclosed |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-11535643-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-27 | — | — | US | disclosed |
| CN-114891059-A | Electromagnetic radiation synthesis method and device of high-density molecular array chip | 深圳市华云智能健康有限公司 | 2022-08-12 | — | — | CN | disclosed |
| US-11008358-B2 | Synthesis of desosamines | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200377542-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-03 | — | — | US | disclosed |
| US-20200347087-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-11-05 | — | — | US | disclosed |
| EP-2661502-B1 | BIOSENSOR FOR DETECTING THE PRESENCE OF PROTEASES AND OPTIONALLY QUANTIFYING THE ENZYMATIC ACTIVITY THEREOF | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2016-03-09 | — | — | EP | disclosed |
| EP-0674710-B1 | Peptides with broad neoplastic specificity | CANCER RES FUND OF CONTRA COST (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6190885-B1 | AMINO ACID SEQUENCES WHICH BIND TO ANTIBODIES SPECIFIC TO HUMAN MILK FAT GLOBULE DIFFERENTIATION ANTIGENS; FOR IN VITRO COMPETITIVE IMMUNOASSAYS | CANCER RESEARCH FUND OF CONTRA COSTA | 2001-02-20 | — | — | US | disclosed |
| US-5804187-A | Modified antibodies with human milk fat globule specificity | CANCER RESEARCH FUND OF CONTRA COSTA (US) | 1998-09-08 | — | — | US | disclosed |
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| US-5663168-A | ADMINISTERING INHIBITORS OF HIV ASPARATATE PROTEASES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0626178-A1 | Use of inhibitors of HIV-protease for the treatment of tumorous diseases | CIBA-GEIGY AG (CH) | 1994-11-30 | — | — | EP | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008358-B2 | Synthesis of desosamines | NANS, GALE, FUT6 | CYP2D6 208/4885KMT2A 1390/4885SRC 4729/4885 |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | FUT6, DDOST, MGAM | CYP2D6 297/4885KMT2A 1230/4885SRC 3087/4885 |
| US-11535643-B2 | Macrolides with modified desosamine sugars and uses thereof | FUT6, MGAM, B3GNT2 | CYP2D6 192/4885KMT2A 1688/4885SRC 4386/4885 |
| US-20200377542-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | FUT6, MGAM, B3GNT2 | CYP2D6 192/4885KMT2A 1688/4885SRC 4386/4885 |
| US-20200347087-A1 | SYNTHESIS OF DESOSAMINES | NANS, GALE, FUT6 | CYP2D6 208/4885KMT2A 1390/4885SRC 4729/4885 |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | FUT6, DDOST, MGAM | CYP2D6 297/4885KMT2A 1230/4885SRC 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.