Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.47 |
| ▸ | APEH | P13798 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172997 | 0.73 | KMT2A (0.54) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL11560494 | 0.73 | PPME1 (0.55) | MAPTKMT2AMEN1PPME1APEH | |
| SCHEMBL11560496 | 0.73 | PPME1 (0.55) | MAPTKMT2AMEN1PPME1APEH | |
| SCHEMBL19506136 | 0.71 | KMT2A (0.53) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL19474912 | 0.71 | KMT2A (0.53) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL19469424 | 0.71 | KMT2A (0.53) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL19474911 | 0.71 | KMT2A (0.53) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL24922336 | 0.70 | MAPT (0.51) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL31118073 | 0.70 | MAPT (0.51) | MAPTKMT2AMEN1MAPK1CYP1A2 | |
| SCHEMBL11153838 | 0.70 | KMT2A (0.72) | MAPTKMT2AMEN1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |