Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.55 |
| ▸ | APEH | P13798 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NEK2 | P51955 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560496 | 1.00 | PPME1 (0.55) | PPME1APEHPKML3MBTL1MEN1 | |
| SCHEMBL19002422 | 0.86 | BTK (0.53) | PPME1APEHPKML3MBTL1MEN1 | |
| SCHEMBL4144065 | 0.82 | NEK2 (0.49) | PPME1APEHPKML3MBTL1MEN1 | |
| SCHEMBL4144063 | 0.82 | NEK2 (0.49) | PPME1APEHPKML3MBTL1MEN1 | |
| SCHEMBL9163842 | 0.81 | PPME1 (0.58) | PPME1APEHPKML3MBTL1MEN1 | |
| SCHEMBL11563220 | 0.80 | PPME1 (0.57) | PPME1APEHPKML3MBTL1MEN1 | |
| SCHEMBL4912425 | 0.80 | PKM (0.79) | PPME1PKML3MBTL1MEN1KMT2A | |
| SCHEMBL4909612 | 0.80 | PKM (0.79) | PPME1PKML3MBTL1MEN1KMT2A | |
| SCHEMBL4909621 | 0.80 | PKM (0.79) | PPME1PKML3MBTL1MEN1KMT2A | |
| SCHEMBL9162141 | 0.80 | ALDH1A1 (0.60) | PKML3MBTL1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |