Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561931 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2SMPD1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL11561969 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2SRCMEN1ALDH1A1CYP1A2 | |
| SCHEMBL11563992 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27955331 | 0.84 | MEN1 (0.39) | SMPD1NR5A1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL19031812 | 0.84 | MEN1 (0.39) | SMPD1NR5A1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9994156 | 0.84 | MEN1 (0.39) | SMPD1NR5A1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL11567432 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL11567414 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4322330 | 0.82 | LMNA (0.36) | NR5A1MEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL11564538 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173630-A | N2 Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1979-11-06 | — | — | US | disclosed |