Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9994156 | 1.00 | MEN1 (0.39) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL19031812 | 1.00 | MEN1 (0.39) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL4322330 | 0.98 | LMNA (0.36) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL4306851 | 0.93 | CYP1A2 (0.41) | LMNACHRM2CYP3A4MAPTNR5A1 | |
| SCHEMBL7274535 | 0.88 | ALDH1A1 (0.36) | MEN1LMNACHRM2MAPTKMT2A | |
| SCHEMBL11565752 | 0.84 | SMN1; SMN2 (0.43) | MEN1KMT2ANR5A1ALDH1A1CYP1A2 | |
| SCHEMBL11561931 | 0.82 | SMN1; SMN2 (0.44) | MEN1KMT2AALDH1A1CYP1A2SMPD1 | |
| SCHEMBL27373651 | 0.82 | MEN1 (0.38) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL17956581 | 0.78 | TLR4 (0.38) | NR5A1TLR4TSHRTP53LTA4H | |
| SCHEMBL6050397 | 0.78 | MEN1 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102351879-B | Heterocyclic-sulfur fused naphthalene diimide compounds, preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2014-04-23 | — | — | CN | disclosed |