Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trichloroethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroethylene SCHEMBL7213332 | 0.89 | — | — | |
| Trichloroethylene SCHEMBL1555224 | 0.85 | — | — | |
| Trichloroethylene SCHEMBL3113029 | 0.85 | TSHR (0.67) | — | |
| Methacrylic Acid SCHEMBL11393188 | 0.82 | TSHR (0.44) | — | |
| Acetic Acid SCHEMBL29039833 | 0.80 | FFAR3 (0.78) | — | |
| Acetic Acid SCHEMBL312459 | 0.80 | — | — | |
| Trichloroethylene SCHEMBL9188425 | 0.78 | TSHR (0.47) | — | |
| Trichloroethylene SCHEMBL27811100 | 0.78 | TSHR (0.47) | — | |
| Butanone SCHEMBL11428980 | 0.78 | ALDH1A1 (0.59) | — | |
| Trichloroethylene SCHEMBL3420295 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166012-A | Method of preparation of electrooptical elements | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-08-28 | — | — | US | disclosed |
| EP-0001016-A1 | Conductive layer for electrophotographic materials and method of making it | SCOTT PAPER COMPANY (US) | 1979-03-07 | — | — | EP | disclosed |
| US-4089645-A | PHOSPHORUS SULFIDE PRETREATMENT | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4063004-A | Metal plating of plastics | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-4048042-A | Apparatus for electroplating plastic insulating cable sheaths | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |