Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517760 | 0.83 | TP53 (0.47) | TP53NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11566296 | 0.79 | NPSR1 (0.48) | TP53NPSR1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL11852171 | 0.78 | TP53 (0.42) | TP53ALDH1A1HTTRXFP1LMNA | |
| SCHEMBL11564288 | 0.76 | S1PR1 (0.41) | NPSR1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL11254225 | 0.76 | TP53 (0.50) | TP53NPSR1ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL11726341 | 0.74 | TP53 (0.49) | TP53NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11315069 | 0.73 | TP53 (0.48) | TP53NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28746553 | 0.73 | MLYCD (0.54) | TP53NPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11796958 | 0.72 | POLB (0.43) | TP53NPSR1EPHX1ALDH1A1MAPT | |
| SCHEMBL11564528 | 0.71 | APEX1 (0.40) | ALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137068-A | Novel ureas | ROUSSEL UCLAF (FR) | 1979-01-30 | — | — | US | claimed |
| US-4137068-A | Novel ureas | ROUSSEL UCLAF (FR) | 1979-01-30 | — | — | US | disclosed |