Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600117 | 0.84 | NPSR1 (0.49) | NPSR1TP53CES2ALDH1A1RORC | |
| SCHEMBL11566293 | 0.79 | TP53 (0.45) | NPSR1TP53CES2ALDH1A1RORC | |
| SCHEMBL11254225 | 0.79 | TP53 (0.50) | NPSR1TP53CES2ALDH1A1TACR1 | |
| Hydrochloric Acid SCHEMBL11726341 | 0.78 | TP53 (0.49) | NPSR1TP53CES2ALDH1A1TACR1 | |
| SCHEMBL11315069 | 0.77 | TP53 (0.48) | NPSR1TP53CES2ALDH1A1TACR1 | |
| SCHEMBL15013852 | 0.76 | HTR2A (0.46) | NPSR1TP53CES2ALDH1A1RORC | |
| SCHEMBL28746553 | 0.76 | MLYCD (0.54) | NPSR1TP53CES2ALDH1A1TACR1 | |
| SCHEMBL9816790 | 0.76 | ALDH1A1 (0.58) | NPSR1TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL11517760 | 0.75 | TP53 (0.47) | NPSR1TP53CES2ALDH1A1TACR1 | |
| SCHEMBL11341652 | 0.74 | NPSR1 (0.46) | NPSR1TP53CES2ALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137068-A | Novel ureas | ROUSSEL UCLAF (FR) | 1979-01-30 | — | — | US | claimed |
| US-4137068-A | Novel ureas | ROUSSEL UCLAF (FR) | 1979-01-30 | — | — | US | disclosed |