Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11567963 | 0.98 | PTGS2 (0.97) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL18168759 | 0.84 | PTGS2 (1.00) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11122035 | 0.84 | NPC1 (0.83) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2121351 | 0.84 | NPC1 (0.83) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7828100 | 0.84 | GAA (1.00) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11518997 | 0.83 | PTGS2 (0.71) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11552621 | 0.83 | PTGS2 (0.97) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28240744 | 0.82 | PTGS2 (1.00) | PTGS2GAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2829063 | 0.81 | PTGS2 (0.68) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9618331 | 0.81 | PTGS2 (0.68) | PTGS2GAASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165428-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1979-08-21 | — | — | US | disclosed |