Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578146 | 0.83 | SLC22A6 (0.39) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL11568977 | 0.83 | FOLH1 (0.52) | SLC22A6LMNATSHRFOLH1CYP2D6 | |
| SCHEMBL8950791 | 0.81 | GABRR1 (0.42) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL6258935 | 0.75 | SLC22A6 (0.43) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL10960275 | 0.72 | SLC22A6 (0.35) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL11641568 | 0.71 | SLC22A6 (0.53) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL30689537 | 0.69 | — | — | |
| SCHEMBL2690498 | 0.69 | — | — | |
| SCHEMBL630577 | 0.69 | TDP1 (0.48) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL2858121 | 0.69 | SLC22A6 (0.43) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141734-A | SUBSTITUTED ORGANIC DI- OR TRISULFIDE ANTIDEPOSIT AGENTS | CIBA-GEIBY AG (CH) | 1979-02-27 | — | — | US | disclosed |