Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566571 | 0.81 | SLC22A6 (0.47) | GABRR1LMNASLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL11568977 | 0.77 | FOLH1 (0.52) | LMNASLC22A6GABRPGABRDCYP1A2 | |
| SCHEMBL7769376 | 0.72 | — | — | |
| SCHEMBL289100 | 0.72 | — | — | |
| SCHEMBL29952120 | 0.72 | — | — | |
| SCHEMBL25297691 | 0.72 | GABRR1 (0.44) | GABRR1LMNASLC22A6GLRA1SLC6A9 | |
| SCHEMBL415749 | 0.72 | — | — | |
| SCHEMBL9619279 | 0.72 | GABRR1 (0.44) | GABRR1LMNASLC22A6GLRA1SLC6A9 | |
| SCHEMBL382930 | 0.72 | — | — | |
| SCHEMBL9578146 | 0.72 | SLC22A6 (0.39) | GABRR1LMNASLC22A6TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532379-A | Biotin containing heterobifunctional cleavable compounds | PIERCE CHEMICAL COMPANY (US) | 1996-07-02 | — | — | US | disclosed |