SCHEMBL11568977

SCHEMBL11568977

O=C(O)CCC(CC(=O)O)SSC(CCC(=O)O)CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.52
TET2 Q6N021 3/20 0.44
KDM4A O75164 2/20 0.44
KDM4C Q9H3R0 2/20 0.44
KDM2A Q9Y2K7 2/20 0.44
TET3 O43151 1/20 0.44
CYP1A2 P05177 2/20 0.42
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42
GABRA3 P34903 2/20 0.42
GABRA2 P47869 2/20 0.42
GABRB2 P47870 2/20 0.42
GABRA4 P48169 2/20 0.42
GABRE P78334 2/20 0.42
GABRA6 Q16445 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566571 0.83 SLC22A6 (0.47) FOLH1LMNAALKBH5SUCNR1EGLN1
SCHEMBL8950791 0.77 GABRR1 (0.42) FOLH1CYP1A2GABRPGABRDGABRA1
SCHEMBL21014419 0.77 GABRP (0.42) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL13950743 0.74 LMNA (0.50) FOLH1CYP1A2GABRPGABRDGABRA1
SCHEMBL9578146 0.74 SLC22A6 (0.39) LMNASLC22A6
SCHEMBL3659066 0.72 FOLH1 (0.56) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL7715710 0.72 FOLH1 (0.56) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL28073368 0.70 SLC22A6 (0.63) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL28240234 0.70 FOLH1 (0.54) FOLH1TET2KDM4AKDM4CKDM2A
SCHEMBL214635 0.70 SLC22A6 (0.63) FOLH1TET2KDM4AKDM4CKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141734-A SUBSTITUTED ORGANIC DI- OR TRISULFIDE ANTIDEPOSIT AGENTS CIBA-GEIBY AG (CH) 1979-02-27 US disclosed