Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 4/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014718 | 0.80 | FDPS (0.32) | FDPS | |
| SCHEMBL4267627 | 0.79 | SMPD1 (0.42) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL21599243 | 0.79 | SMPD1 (0.42) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL3855455 | 0.79 | ODC1 (0.32) | TSHRDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL17350823 | 0.77 | SMPD1 (0.41) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL13970557 | 0.77 | OPRM1 (0.41) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL18894066 | 0.77 | OPRM1 (0.41) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL14246754 | 0.77 | FDPS (0.45) | SMPD1FDPSGGPS1 | |
| SCHEMBL11230098 | 0.77 | OPRM1 (0.41) | SMPD1FDPSTSHRTHRBDNM1 | |
| SCHEMBL8368936 | 0.76 | FDPS (0.40) | SMPD1FDPSTSHRTHRBDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002258-A2 | Hydantoin derivatives and salts thereof, their synthesis and intermediates, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-06-13 | — | — | EP | disclosed |