Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934862 | 0.94 | MAPT (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL5494961 | 0.89 | TDP1 (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL28531572 | 0.85 | POLB (0.51) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL656178 | 0.84 | AR (0.53) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL1263762 | 0.84 | POLB (0.47) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL6049252 | 0.82 | TDP1 (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL9002377 | 0.82 | AR (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL31590227 | 0.82 | PTGS1 (0.59) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL6141129 | 0.81 | TDP1 (0.52) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL19021801 | 0.80 | USP2 (0.62) | MAPTPOLBLMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179337-A | POLYALKYLENE GLYCOL LINKED TO POLYPEPTIDE THROUGH COUPLER | RESEARCH CORPORATION TECHNOLOGIES, INC., A NOT-FOR-PROFIT, NON-STOCK CORP. OF DE | 1979-12-18 | — | — | US | disclosed |