Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566950 | 0.94 | MAPT (0.50) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL28531572 | 0.90 | POLB (0.51) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL656178 | 0.90 | AR (0.53) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL9002377 | 0.88 | AR (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL6049252 | 0.88 | TDP1 (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL5494961 | 0.87 | TDP1 (0.55) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL6141129 | 0.86 | TDP1 (0.52) | MAPTPOLBLMNANPSR1ADRB2 | |
| SCHEMBL188449 | 0.83 | HIF1A (0.65) | POLBALDH1A1TDP1SMN1; SMN2HTT | |
| SCHEMBL16314531 | 0.83 | CA12 (0.64) | MAPTADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL8479002 | 0.83 | TDP1 (0.48) | MAPTPOLBLMNANPSR1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303742-B1 | CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. | KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-0012925-B1 | QUINOLON-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-10 | — | — | EP | disclosed |
| US-4289777-A | Quinolonecarboxylic acid derivatives and pharmaceutical preparations thereof for treatment of an allergic disease of the respiratory tract | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |
| EP-0012925-A1 | Quinolon-carboxylic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |