Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24049735 | 1.00 | CTSK (0.57) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL11567669 | 0.93 | CTSK (0.53) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL8530164 | 0.93 | PSEN1 (0.59) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL16483180 | 0.93 | CTSK (0.55) | CTSKPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8137308 | 0.90 | MEN1 (0.55) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL4576421 | 0.90 | CTSK (0.65) | CTSKCTSB | |
| SCHEMBL16984912 | 0.90 | CTSK (0.65) | CTSKCTSB | |
| SCHEMBL25977611 | 0.90 | CTSK (0.65) | CTSKCTSB | |
| SCHEMBL13519505 | 0.90 | CTSK (0.64) | CTSKCTSBPOLBGPR55MEN1 | |
| SCHEMBL12214454 | 0.90 | CTSK (0.64) | CTSKCTSBPOLBGPR55MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |