Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 11/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24049735 | 0.93 | CTSK (0.57) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL11566964 | 0.93 | CTSK (0.57) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL11568495 | 0.92 | BACE1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11569823 | 0.92 | BACE1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10877170 | 0.90 | PSEN1 (0.52) | CTSKPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11567448 | 0.87 | CTSK (0.55) | CTSKCTSB | |
| SCHEMBL8530164 | 0.87 | PSEN1 (0.59) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL16483180 | 0.86 | CTSK (0.55) | CTSKPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31107818 | 0.86 | CTSK (0.48) | CTSKCTSBPSEN1PSEN2APH1B | |
| SCHEMBL8137308 | 0.84 | MEN1 (0.55) | CTSKCTSBPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |