Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319008 | 0.95 | MRGPRX4 (0.49) | MRGPRX4PPARAPPARDCYSLTR2CYSLTR1 | |
| SCHEMBL11567730 | 0.91 | MRGPRX4 (0.46) | MRGPRX4PPARACYSLTR2CYSLTR1S1PR4 | |
| SCHEMBL11408460 | 0.89 | L3MBTL1 (0.53) | MRGPRX4PPARACYSLTR2CYSLTR1S1PR4 | |
| SCHEMBL11566926 | 0.89 | L3MBTL1 (0.53) | MRGPRX4PPARACYSLTR2CYSLTR1S1PR4 | |
| SCHEMBL11566169 | 0.89 | L3MBTL1 (0.53) | MRGPRX4PPARACYSLTR2CYSLTR1S1PR4 | |
| SCHEMBL11564232 | 0.89 | L3MBTL1 (0.53) | MRGPRX4PPARACYSLTR2CYSLTR1S1PR4 | |
| SCHEMBL11566141 | 0.89 | L3MBTL1 (0.53) | MRGPRX4PPARACYSLTR2CYSLTR1S1PR4 | |
| SCHEMBL11567003 | 0.87 | L3MBTL1 (0.54) | MRGPRX4PPARAS1PR4MAPTTDP1 | |
| SCHEMBL11309550 | 0.85 | MRGPRX4 (0.47) | MRGPRX4PPARAPPARDCYSLTR2CYSLTR1 | |
| Arildone SCHEMBL146967 | 0.85 | MRGPRX4 (0.47) | MRGPRX4PPARAPPARDCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171376-A | Aryloxyalkyl keto-esters | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |