Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 11/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598039 | 0.93 | VCAM1 (0.52) | VCAM1CA1CA2PTGS1MAPT | |
| SCHEMBL11598590 | 0.88 | VCAM1 (0.48) | VCAM1CA1CA2PTGS1MAPT | |
| SCHEMBL28159896 | 0.85 | VCAM1 (0.68) | VCAM1CA1CA2MAPTHPN | |
| SCHEMBL974774 | 0.84 | VCAM1 (0.56) | VCAM1CA1CA2PTGS1MAPT | |
| SCHEMBL38445 | 0.81 | VCAM1 (0.60) | VCAM1CA1CA2PTGS1MAPT | |
| SCHEMBL1577556 | 0.79 | VCAM1 (0.61) | VCAM1CA1CA2PTGS1MAPT | |
| SCHEMBL27695001 | 0.79 | VCAM1 (0.52) | VCAM1CA1CA2MAPTHPN | |
| SCHEMBL237358 | 0.79 | VCAM1 (0.50) | VCAM1CA1CA2GAASMN1; SMN2 | |
| SCHEMBL1886267 | 0.79 | VCAM1 (0.50) | VCAM1CA1CA2GAASMN1; SMN2 | |
| SCHEMBL11564291 | 0.79 | VCAM1 (0.47) | VCAM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173574-A | 3,5-Ditertiary alkyl-4-hydroxyphenyl (alkyl) 6-acyloxy-4-thia hexanoates and hexenamides as antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-11-06 | — | — | US | disclosed |
| US-4093591-A | FOR NATURAL RUBBER AND HOMO- AND COPOLYMERS OF MONO- AND DIOLEFINS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-06-06 | — | — | US | disclosed |