Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21526090 | 0.85 | NPC1 (0.48) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL5275709 | 0.83 | PPARG (0.54) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL11859865 | 0.83 | RAB9A (0.47) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL21400206 | 0.81 | NPC1 (0.46) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL31329429 | 0.81 | AKR1B1 (0.52) | IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13235838 | 0.81 | NPC1 (0.46) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL11565631 | 0.81 | AKR1B1 (0.53) | ALDH1A1MAOASMN1; SMN2HTT | |
| SCHEMBL14271140 | 0.80 | SLC6A2 (0.47) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL28876911 | 0.80 | PPARG (0.51) | NPC1RAB9APPARGPPARAALDH1A1 | |
| SCHEMBL14950912 | 0.77 | ALDH1A1 (0.45) | NPC1RAB9APPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |