Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.47 |
| ▸ | NPY1R | P25929 | 9/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.47 |
| ▸ | NPY2R | P49146 | 5/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31643173 | 1.00 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RBACE1 | |
| SCHEMBL11567327 | 1.00 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RBACE1 | |
| SCHEMBL11569777 | 1.00 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RBACE1 | |
| SCHEMBL29774197 | 0.94 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29658786 | 0.94 | FURIN (0.38) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30988493 | 0.91 | NPY4R (0.43) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30085019 | 0.91 | NPY4R (0.43) | NPY4RNPY1RNPY5RNPY2RCTSD | |
| SCHEMBL31064839 | 0.90 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29978051 | 0.90 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30140870 | 0.89 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |