SCHEMBL30085019

CC[C@H](C)[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.43

▸	NPY1R	P25929	9/20	0.43

▸	NPY5R	Q15761	8/20	0.43

▸	NPY2R	P49146	5/20	0.43

▸	VIPR2	P41587	1/20	0.39

▸	MAPK8	P45983	1/20	0.39

▸	MAPK9	P45984	1/20	0.39

▸	MAPK10	P53779	1/20	0.39

▸	VIPR1	P32241	1/20	0.38

▸	CTSD	P07339	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29995282	0.94	NPY4R (0.45)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30239619	0.92	NPY4R (0.43)	NPY4RNPY1RNPY5RNPY2RVIPR2
SCHEMBL31643173	0.91	NPY4R (0.47)	NPY4RNPY1RNPY5RNPY2RCTSD
SCHEMBL11567327	0.91	NPY4R (0.47)	NPY4RNPY1RNPY5RNPY2RCTSD
SCHEMBL11567334	0.91	NPY4R (0.47)	NPY4RNPY1RNPY5RNPY2RCTSD
SCHEMBL11569777	0.91	NPY4R (0.47)	NPY4RNPY1RNPY5RNPY2RCTSD
SCHEMBL30093085	0.90	NPY4R (0.45)	NPY4RNPY1RNPY5RNPY2RCTSD
SCHEMBL29679830	0.90	MAPK8 (0.46)	NPY4RNPY1RNPY5RNPY2RVIPR2
SCHEMBL31514354	0.90	RXFP1 (0.46)	NPY4RNPY1RNPY5RNPY2RVIPR2
SCHEMBL29777419	0.88	ENPEP (0.48)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4090383-A2	IL2 ORTHOLOGS AND METHODS OF USE	Synthekine, Inc. (US)	2022-11-23	—	—	EP	disclosed