SCHEMBL29658786

SCHEMBL29658786

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nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 5/20 0.38
▸ NPY4R P50391 10/20 0.38
▸ NPY1R P25929 7/20 0.38
▸ NPY2R P49146 5/20 0.38
▸ NPY5R Q15761 5/20 0.38
▸ NOD1 Q9Y239 2/20 0.37
▸ CTSC P53634 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540572 0.94 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL11567334 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31643173 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL11569777 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL11567327 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31673514 0.93 FURIN (0.39) FURINNPY4RNPY1RNPY2RNPY5R
SCHEMBL9819642 0.93 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL9819648 0.93 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL29697049 0.93 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL31110537 0.91 FURIN (0.42) FURINNPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix CASE WESTERN RESERVE UNIVERSITY (US) 2026-03-17 — — US disclosed
CN-116555283-A Japanese larch LkZFP36 gene and protein encoded by same, application, over-expression vector and acquisition method 东北林业大学 2023-08-08 — — CN disclosed
US-20220160903-A1 PEPTIDE PET/SPECT PROBES SPECIFIC TO ONCOPROTEINS IN TUMOR EXTRACELLULAR MATRIX CASE WESTERN RESERVE UNIVERSITY 2022-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160903-A1 PEPTIDE PET/SPECT PROBES SPECIFIC TO ONCOPROTEINS IN TUMOR EXTRACELLULAR MATRIX FN1, EDNRB, NGLY1 FURIN 848/4885NPY4R 2610/4885NPY1R 795/4885
US-12576168-B2 Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix FN1, INHA, EDNRB FURIN 1511/4885NPY4R 2238/4885NPY1R 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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