Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743873 | 0.79 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL17084188 | 0.76 | AHR (0.46) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL1988446 | 0.76 | AHR (0.46) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL17069194 | 0.76 | AHR (0.46) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL11070316 | 0.76 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL10867874 | 0.73 | AHR (0.48) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL6991220 | 0.71 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2AHRPNMT | |
| SCHEMBL5789630 | 0.71 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2AHRIDO1 | |
| SCHEMBL4631310 | 0.71 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL254524 | 0.71 | AHR (0.50) | SLC6A3SLC6A4SLC6A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |