Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL10347735 | 0.95 | ALDH1A1 (0.49) | AHRSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL14670465 | 0.85 | AHR (0.67) | AHRSLC6A4SLC6A2SLC6A3CYP1B1 | |
| SCHEMBL5367586 | 0.84 | IDO1 (0.45) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| SCHEMBL10867874 | 0.82 | AHR (0.48) | AHRSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL13524616 | 0.81 | AHR (0.54) | AHRALDH1A1HTTSMN1; SMN2TP53 | |
| SCHEMBL4458063 | 0.80 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL17084188 | 0.80 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL22964332 | 0.80 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL22032277 | 0.80 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL2951028 | 0.80 | AHR (0.46) | AHRSLC6A4SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 703 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121192-B1 | ANALYTICAL TEST COMPOSITION, DEVICE, METHOD FOR ITS PREPARATION AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCE | MILES INC. (US) | 1990-06-27 | — | — | EP | claimed |
| US-12043613-B2 | Inhibitors of SARM1 | DISARM THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043613-B2 | Inhibitors of SARM1 | DISARM THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| EP-3863638-B1 | PHOSPHODIESTERASE INHIBITORS | UNIV NEBRASKA (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2003101382-A2 | COMPOUNDS USEFUL IN THE TREATMENT OF ANTHRAX AND INHIBITING LETHAL FACTOR | MERCK & CO., INC. (US) | 2003-12-11 | — | — | WO | disclosed |
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |
| EP-0121192-B1 | ANALYTICAL TEST COMPOSITION, DEVICE, METHOD FOR ITS PREPARATION AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCE | MILES INC. (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4568777-A | GAS PHASE REACTION WITH PENTASIL, MORDENITE AND FAUJASITE ZEOLITE | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-04 | — | — | US | disclosed |
| EP-0121192-A2 | Analytical test composition, device, method for its preparation and method for the determination of peroxidatively active substance | MILES INC. (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4447542-A | USING SUBSTITUTED CUMENE HYDROPEROXIDE AND INDICATOR; COLORIMETRIC ANALYSIS | MILES LABORATORIES, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4005218-A | Antiparasitic salicylanilide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-01-25 | — | — | US | disclosed |
| US-3954876-A | HALOCUMENE OXIDATION CATALYZED BY METAL PHTHALOCYANINE COMPLEX | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | RNASEH1, RNASEL, DNASE1 | AHR 1150/4885SLC6A4 3108/4885SLC6A2 3980/4885 |
| US-12043613-B2 | Inhibitors of SARM1 | SARM1, SMN1; SMN2, SARNP | AHR 4440/4885SLC6A4 3410/4885SLC6A2 2958/4885 |
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | IL4, IL2, IL4I1 | AHR 2128/4885SLC6A4 2751/4885SLC6A2 4855/4885 |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | ACE2, ACE, TMPRSS2 | AHR 2847/4885SLC6A4 4659/4885SLC6A2 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.