Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.58 |
| ▸ | RELA | Q04206 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708400 | 0.91 | NPC1 (0.66) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL1744060 | 0.86 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL11562017 | 0.85 | KDM4E (0.61) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL8534417 | 0.85 | MAPT (0.79) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL14878460 | 0.82 | MAPT (0.81) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL11141442 | 0.81 | NPC1 (0.57) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL9797066 | 0.81 | KDM4E (0.71) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL1105986 | 0.81 | NPC1 (1.00) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL12408909 | 0.81 | MAPT (0.84) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 | |
| SCHEMBL16602327 | 0.80 | NPC1 (0.68) | RAB9ASMN1; SMN2NPC1KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169837-A | BICHROMOPHORIC BENZOXAZOLE ULTRAVIOLET STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4029670-A | Polychromophoric heterocyclic ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1977-06-14 | — | — | US | disclosed |