Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CDH1 | P12830 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708400 | 0.91 | NPC1 (0.66) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL1744060 | 0.86 | SMN1; SMN2 (0.77) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11567645 | 0.85 | RAB9A (0.68) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8534417 | 0.85 | MAPT (0.79) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8122840 | 0.83 | SENP7 (0.57) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11147962 | 0.83 | NPC1 (0.68) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL5756695 | 0.82 | GAA (0.55) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL11215209 | 0.81 | NPC1 (0.66) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11141442 | 0.81 | NPC1 (0.57) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL9797066 | 0.81 | KDM4E (0.71) | KDM4ESMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169837-A | BICHROMOPHORIC BENZOXAZOLE ULTRAVIOLET STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4029670-A | Polychromophoric heterocyclic ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1977-06-14 | — | — | US | disclosed |