Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030901 | 1.00 | CTSK (0.57) | CTSKELANEMMEECE1CTSL | |
| SCHEMBL11568471 | 1.00 | CTSK (0.57) | CTSKELANEMMEECE1CTSL | |
| SCHEMBL11305760 | 0.99 | CTSK (0.56) | CTSKELANEMMEECE1CTSL | |
| SCHEMBL11307484 | 0.92 | CTSK (0.53) | CTSKELANEMMEECE1 | |
| SCHEMBL4163321 | 0.90 | ELANE (0.60) | CTSKELANEMMEECE1CTSL | |
| SCHEMBL8740045 | 0.90 | ELANE (0.60) | CTSKELANEMMEECE1CTSL | |
| SCHEMBL11567174 | 0.90 | ELANE (0.60) | CTSKELANEMMEECE1CTSL | |
| SCHEMBL11310090 | 0.90 | CTSK (0.57) | CTSKMMEECE1CTSLCTSB | |
| SCHEMBL11301087 | 0.90 | CTSK (0.53) | CTSKMMEECE1CTSLCTSB | |
| SCHEMBL11300848 | 0.88 | CTSK (0.60) | CTSKMMEECE1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134972-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4127649-A | PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4100275-A | PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-07-11 | — | — | US | disclosed |