Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | KYNU | Q16719 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163321 | 1.00 | ELANE (0.60) | ELANEATMPRTN3ACE2CTSK | |
| SCHEMBL11567174 | 1.00 | ELANE (0.60) | ELANEATMPRTN3ACE2CTSK | |
| SCHEMBL11567663 | 0.90 | CTSK (0.57) | ELANEATMPRTN3CTSKECE1 | |
| SCHEMBL11030901 | 0.90 | CTSK (0.57) | ELANEATMPRTN3CTSKECE1 | |
| SCHEMBL11568471 | 0.90 | CTSK (0.57) | ELANEATMPRTN3CTSKECE1 | |
| SCHEMBL8587097 | 0.90 | ELANE (0.59) | ELANEATMPRTN3ACE2CTSK | |
| SCHEMBL11305760 | 0.89 | CTSK (0.56) | ELANEPRTN3CTSKECE1MME | |
| SCHEMBL6923368 | 0.87 | KYNU (0.57) | ELANEATMPRTN3ACE2CTSK | |
| SCHEMBL6923362 | 0.87 | KYNU (0.57) | ELANEATMPRTN3ACE2CTSK | |
| SCHEMBL11304013 | 0.87 | CTSK (0.55) | ELANECTSKKYNUCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1187360-C | Phosphonic acid derivs, having carboxypeptidase B inhibitory activity | MEIJI SEIKA KAISHA (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1373766-A | Phosphonic acid derivatives having carboxypeptidase B inhibitory activity | MEIJI SEIKA KAISHA (JP) | 2002-10-09 | — | — | CN | disclosed |
| US-5703263-A | USEFUL AS ANTIBIOTICS AND/OR AS INTERMEDIATES IN THE PREPARATION OF PHOSPHORUS-CONTAINING ANALOGS OF PEPTIDES | MONSANTO COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5654462-A | CATALYTIC HYDROGENATION OF OLEFINS; ANTIBIOTICS; ENZYME INHIBITOR | MONSANTO COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| US-5321153-A | Asymetric hydrogenation | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-4134972-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4127649-A | PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4100275-A | PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-07-11 | — | — | US | disclosed |