Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31676582 | 0.86 | PTGS2 (0.55) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| SCHEMBL17213443 | 0.80 | HPGD (0.62) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| SCHEMBL4555534 | 0.79 | HPGD (0.60) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2695169 | 0.78 | HPGD (0.58) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| SCHEMBL2113098 | 0.77 | HPGD (0.57) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| SCHEMBL4027589 | 0.76 | CA1 (0.51) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| SCHEMBL11217740 | 0.75 | PTGIR (0.53) | HPGDTP53SMN1; SMN2PTGS2HSP90AA1 | |
| SCHEMBL2694791 | 0.74 | HPGD (0.54) | HPGDTP53NPC1MAOBSMN1; SMN2 | |
| SCHEMBL11311239 | 0.74 | HPGD (0.54) | HPGDTP53NPC1SMN1; SMN2MAPT | |
| SCHEMBL4555528 | 0.74 | HPGD (0.54) | HPGDTP53NPC1MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165428-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1979-08-21 | — | — | US | disclosed |