Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568110 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29815682 | 0.96 | ALDH1A1 (0.50) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL30050920 | 0.94 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29531487 | 0.94 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL30423437 | 0.94 | ALDH1A1 (0.51) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29365416 | 0.91 | ALDH1A1 (0.49) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL8656320 | 0.90 | ALDH1A1 (0.45) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL8656318 | 0.90 | ALDH1A1 (0.45) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL29777830 | 0.89 | MME (0.46) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL8978213 | 0.88 | FOLH1 (0.51) | BACE1CTSDFOLH1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |