SCHEMBL8978213

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O

nearest known ligand 0.51

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	4/20	0.51

▸	BACE1	P56817	16/20	0.50

▸	BACE2	Q9Y5Z0	3/20	0.50

▸	CTSD	P07339	4/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29609184	0.90	BACE1 (0.56)	FOLH1BACE1BACE2CTSD
SCHEMBL30570973	0.88	FURIN (0.46)	FOLH1BACE1BACE2CTSD
SCHEMBL29416042	0.88	NOD1 (0.46)	FOLH1BACE1BACE2CTSD
SCHEMBL11568115	0.88	ALDH1A1 (0.46)	FOLH1BACE1BACE2CTSD
SCHEMBL11568110	0.88	ALDH1A1 (0.46)	FOLH1BACE1BACE2CTSD
SCHEMBL29386735	0.88	FOLH1 (0.50)	FOLH1BACE1CTSD
SCHEMBL30327351	0.88	FOLH1 (0.65)	FOLH1
SCHEMBL29413764	0.87	BACE1 (0.47)	FOLH1BACE1BACE2CTSD
SCHEMBL31394953	0.87	FOLH1 (0.52)	FOLH1BACE1BACE2CTSD
SCHEMBL38665586	0.85	BACE1 (0.63)	BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5516657-A	Baculovirus vectors for expression of secretory and membrane-bound proteins	CAMBRIDGE BIOTECH CORPORATION (US)	1996-05-14	—	—	US	disclosed