Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372858 | 0.77 | TBXA2R (0.43) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11367013 | 0.77 | TBXA2R (0.43) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11366261 | 0.74 | TBXA2R (0.46) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11847227 | 0.74 | PTGFR (0.32) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11374469 | 0.72 | PTGER4 (0.44) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11741757 | 0.71 | PTGFR (0.40) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11724527 | 0.70 | TBXA2R (0.34) | PTGFRLMNAHPGDTSHRMAPK1 | |
| SCHEMBL11717810 | 0.70 | TBXA2R (0.32) | PTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL11508719 | 0.68 | TBXA2R (0.31) | PTGFRALDH1A1TBXA2R | |
| SCHEMBL11508721 | 0.68 | TBXA2R (0.31) | PTGFRALDH1A1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000207-A1 | Prostaglandin derivatives, their preparation and pharmaceutical compositions and intermediates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-01-10 | — | — | EP | disclosed |