Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.34 |
| ▸ | PTGFR | P43088 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717810 | 0.92 | TBXA2R (0.32) | TBXA2RPTGFRPTGER1PTGER3 | |
| SCHEMBL11847227 | 0.91 | PTGFR (0.32) | TBXA2RPTGFRPGRADORA3ADRA2C | |
| SCHEMBL11775319 | 0.87 | ALOX5 (0.32) | — | |
| SCHEMBL11633368 | 0.86 | PTGFR (0.35) | TBXA2RPTGFRLMNAHPGDTSHR | |
| SCHEMBL11780570 | 0.86 | PTGFR (0.35) | TBXA2RPTGFRLMNAHPGDTSHR | |
| SCHEMBL11759785 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11717734 | 0.79 | — | — | |
| SCHEMBL11778033 | 0.79 | — | — | |
| SCHEMBL11652695 | 0.79 | PTGFR (0.30) | PTGFR | |
| SCHEMBL11846710 | 0.78 | TBXA2R (0.31) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061865-A | Prostaglandin analogues | ONO PHARMACEUTICAL COMPANY (JA) | 1977-12-06 | — | — | US | disclosed |
| US-3989736-A | INCREASED DURATION OF ACTION | PFIZER INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3962312-A | 9,11,15-Trihydroxy prost-5-enoic acid analogues | ONO PHARMACEUTICAL COMPANY (JA) | 1976-06-08 | — | — | US | disclosed |