Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568253 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL31518662 | 0.94 | ALDH1A1 (0.49) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL30051624 | 0.93 | ALDH1A1 (0.50) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL29663577 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL11568115 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL11568110 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL30997408 | 0.85 | MME (0.44) | — | |
| SCHEMBL11568054 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL11570005 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL11569994 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |