Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.82 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.82 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.82 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565181 | 0.90 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11569060 | 0.88 | OPRM1 (0.84) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| Hydrochloric Acid SCHEMBL11565087 | 0.87 | OPRM1 (0.76) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11803611 | 0.86 | OPRM1 (0.62) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11559506 | 0.84 | OPRM1 (0.88) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11565724 | 0.84 | OPRM1 (0.88) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11566771 | 0.83 | OPRM1 (0.86) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11798037 | 0.83 | OPRM1 (0.86) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11564673 | 0.83 | OPRM1 (0.86) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| Citric Acid SCHEMBL10971572 | 0.81 | OPRM1 (0.70) | OPRM1OPRD1OPRK1SLC22A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |