SCHEMBL11565181

SCHEMBL11565181

CCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 1.00
OPRD1 P41143 4/20 1.00
OPRK1 P41145 2/20 1.00
SLC22A1 O15245 1/20 0.75
ABCB1 P08183 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11559506 0.94 OPRM1 (0.88) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11565724 0.94 OPRM1 (0.88) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11798037 0.93 OPRM1 (0.86) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11564673 0.93 OPRM1 (0.86) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11566771 0.93 OPRM1 (0.86) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11569060 0.92 OPRM1 (0.84) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11565395 0.91 OPRM1 (0.84) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11568358 0.90 OPRM1 (0.82) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11569132 0.90 OPRM1 (0.80) OPRM1OPRD1OPRK1SLC22A1ABCB1
SCHEMBL11565063 0.89 OPRM1 (0.81) OPRM1OPRD1OPRK1SLC22A1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3998834-A ANALGESICS JANSSEN PHARMACEUTICA N.V. (BE) 1976-12-21 US claimed
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 US disclosed
US-12529695-B2 Fentanyl analogue detection methods and kits thereof VERITEQUE USA, INC. (US) 2026-01-20 US disclosed
US-20250366979-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 US disclosed
US-20250366978-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 US disclosed
US-20250251323-A1 COLLECTION PROBE AND METHODS OF USE THEREOF BAYLOR COLLEGE OF MEDICINE 2025-08-07 US disclosed
WO-2025128946-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF THE METHODIST HOSPITAL (US) 2025-06-19 WO disclosed
EP-4536138-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF The Methodist Hospital (US) 2025-04-16 EP disclosed
EP-4536139-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF The Methodist Hospital (US) 2025-04-16 EP disclosed
EP-4507825-A1 COLLECTION PROBE AND METHODS OF USE THEREOF Board of Regents, The University of Texas System (US) 2025-02-19 EP disclosed
US-20220390439-A1 FENTANYL ANALOGUE DETECTION METHODS AND KITS THEREOF VERITEQUE USA, INC. 2022-12-08 US disclosed
US-20220226446-A1 NEUROTOXIN COMPOSITIONS FOR USE IN IMPROVING LUNG FUNCTION BONTI INC (US) 2022-07-21 US disclosed
US-20210093557-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE ADAPT PHARMA LTD (IE) 2021-04-01 US disclosed
US-20200352917-A1 MEDICATED SPRAY FOR TREATMENT OF SUBSTANCE ABUSE, OVERDOSE, ADDICTION AND IMPULSE CONTROL DISORDERS GOOBERMAN LANCE L (US) 2020-11-12 US disclosed
US-20200030229-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE Adapt Pharma Limited 2020-01-30 US disclosed
US-20190015323-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE Adaph Pharma Limited 2019-01-17 US disclosed
US-20170071851-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE INDIVIOR UK LIMITED (GB) 2017-03-16 US disclosed
US-20170071851-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE INDIVIOR UK LIMITED (GB) 2017-03-16 US disclosed
US-4179569-A ANALGESIC INTERMEDIATES JANSSEN PHARMACEUTICA N.V. (BE) 1979-12-18 US disclosed
US-3998834-A ANALGESICS JANSSEN PHARMACEUTICA N.V. (BE) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170071851-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885
US-20210093557-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885
US-12529695-B2 Fentanyl analogue detection methods and kits thereof CA13, CA2, CA12 OPRM1 24/4885OPRD1 6/4885OPRK1 19/4885
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF PFKP, PBK, MYLK OPRM1 4810/4885OPRD1 4518/4885OPRK1 2862/4885
US-20190015323-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885
US-20200030229-A1 NASAL DRUG PRODUCTS AND METHODS OF THEIR USE OPRL1, OPRM1, OPRK1 OPRM1 2/4885OPRD1 4/4885OPRK1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.