Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.67 |
| ▸ | CTSK | P43235 | 9/20 | 0.67 |
| ▸ | CTSB | P07858 | 4/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516385 | 0.89 | CTSS (0.68) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20516388 | 0.89 | CTSS (0.68) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL6161119 | 0.87 | CTSS (0.70) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL19513108 | 0.87 | CTSS (0.70) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3004471 | 0.86 | CTSS (0.71) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3004474 | 0.86 | CTSS (0.71) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL5556757 | 0.86 | CTSS (0.71) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL11569657 | 0.85 | CCKBR (0.62) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL20799203 | 0.85 | CTSS (0.62) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL6163823 | 0.84 | CTSS (0.73) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172130-A | α-AMINOACYL CONTAINING NEW PEPTIDES WITH GASTRIN EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1979-10-23 | — | — | US | disclosed |