Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569474 | 0.89 | CYP1A2 (0.68) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| SCHEMBL11570810 | 0.86 | PPARA (0.59) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| SCHEMBL11571618 | 0.85 | PPARA (0.65) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| Clofibrate SCHEMBL3953607 | 0.81 | PPARA (1.00) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| Clofibrate SCHEMBL2356 | 0.81 | PPARA (1.00) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| SCHEMBL11074943 | 0.80 | PPARA (0.86) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| SCHEMBL11449590 | 0.80 | PPARA (0.71) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| Clofibrate SCHEMBL11184809 | 0.79 | PPARA (0.97) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| Clofibrate SCHEMBL11187010 | 0.79 | PPARA (0.97) | PPARACYP1A2CYP3A4ABCB11TSHR | |
| Clofibrate SCHEMBL3345 | 0.79 | PPARA (0.97) | PPARACYP1A2CYP3A4ABCB11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |