Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | PPARA | Q07869 | 3/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568564 | 0.89 | PPARA (0.65) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| SCHEMBL11449590 | 0.86 | PPARA (0.71) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| SCHEMBL11569812 | 0.86 | PPARA (0.62) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| SCHEMBL11458497 | 0.83 | PPARA (0.67) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| Clofibrate SCHEMBL2356 | 0.83 | PPARA (1.00) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| Clofibrate SCHEMBL3953607 | 0.83 | PPARA (1.00) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| Hydrochloric Acid SCHEMBL11448560 | 0.82 | PPARA (0.65) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| SCHEMBL11074943 | 0.81 | PPARA (0.86) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| Clofibrate SCHEMBL11187010 | 0.81 | PPARA (0.97) | CYP1A2CYP3A4PPARAABCB11TSHR | |
| Clofibrate SCHEMBL3345 | 0.81 | PPARA (0.97) | CYP1A2CYP3A4PPARAABCB11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |