Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.55 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 6/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.50 |
| ▸ | NPY1R | P25929 | 5/20 | 0.50 |
| ▸ | NPY2R | P49146 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195747 | 0.89 | IL1RN (0.56) | BACE1BACE2IL1RNERAP2NPY4R | |
| SCHEMBL1372552 | 0.88 | OPRD1 (0.56) | BACE1BACE2OPRD1OPRM1OPRK1 | |
| SCHEMBL11566909 | 0.88 | BACE1 (0.51) | BACE1BACE2PTPN1IL1RNERAP2 | |
| SCHEMBL31696295 | 0.88 | BACE1 (0.61) | BACE1BACE2PTPN1IL1RNERAP2 | |
| SCHEMBL30123009 | 0.85 | NAALAD2 (0.61) | BACE1BACE2IL1RNERAP2NPY4R | |
| SCHEMBL29973288 | 0.85 | BACE1 (0.65) | BACE1BACE2PTPN1NPY4RNPY1R | |
| SCHEMBL31363027 | 0.85 | OPRD1 (0.56) | BACE1BACE2NPY4ROPRD1OPRM1 | |
| SCHEMBL6516934 | 0.84 | BACE1 (0.57) | BACE1BACE2PTPN1NPY4RNPY1R | |
| SCHEMBL30798183 | 0.83 | BACE1 (0.63) | BACE1BACE2OPRD1 | |
| SCHEMBL29616324 | 0.82 | BACE1 (0.58) | BACE1BACE2PTPN1IL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164571-A | Medicament which antagonizes the action of gastrin and related polypeptides | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1979-08-14 | — | — | US | claimed |
| US-4164571-A | Medicament which antagonizes the action of gastrin and related polypeptides | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1979-08-14 | — | — | US | disclosed |