Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | CCKAR | P32238 | 3/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182117 | 0.89 | OPRD1 (0.64) | OPRD1OPRM1OPRK1 | |
| SCHEMBL11568629 | 0.88 | BACE1 (0.55) | OPRD1OPRM1OPRK1BACE1BACE2 | |
| SCHEMBL1374934 | 0.86 | OPRD1 (0.59) | OPRD1OPRM1OPRK1CCKARCCKBR | |
| SCHEMBL14706288 | 0.84 | NAALAD2 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29658003 | 0.84 | OPRD1 (0.52) | OPRD1OPRM1OPRK1BACE1BACE2 | |
| SCHEMBL16621773 | 0.83 | NAALAD2 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29538675 | 0.83 | NAALAD2 (0.66) | — | |
| SCHEMBL11886066 | 0.83 | NAALAD2 (0.66) | — | |
| SCHEMBL6378283 | 0.83 | NAALAD2 (0.66) | — | |
| SCHEMBL2195747 | 0.82 | IL1RN (0.56) | OPRD1OPRM1OPRK1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160263235-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC (CA) | 2016-09-15 | — | — | US | disclosed |
| US-20110288011-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263235-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | VIP, SLC1A5, SLC47A1 | OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885 |
| US-20110288011-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | VIP, SLC1A5, SLC47A1 | OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.