Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566910 | 0.88 | MAPK1 (0.49) | GPR88TYRHPGDALOX5NR1H4 | |
| SCHEMBL11565256 | 0.88 | CSNK1D (0.47) | TYRMAPTPOLBHPGDRAB9A | |
| SCHEMBL9059711 | 0.84 | PTPN11 (0.47) | GPR88MAPTRAB9AALOX5MAOB | |
| SCHEMBL8983949 | 0.83 | TYR (0.46) | TYRKAT6AMAPTPOLBMEN1 | |
| SCHEMBL11559419 | 0.83 | GAA (0.46) | TYRMAOBLMNA | |
| SCHEMBL11551597 | 0.82 | PTPN11 (0.51) | GPR88 | |
| SCHEMBL11558507 | 0.82 | HPGD (0.50) | TYRMAPTPOLBHPGDRAB9A | |
| SCHEMBL787715 | 0.77 | KDM4E (0.41) | KAT6ASIRT2MAPTMAOBMDM2 | |
| SCHEMBL3453799 | 0.77 | TYR (0.59) | TYRMAPTRAB9AALOX5MEN1 | |
| SCHEMBL11833120 | 0.76 | TYR (0.46) | TYRMAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |