SCHEMBL11565256

SCHEMBL11565256

CCOc1ccc(C(C(=O)C(c2ccccc2)c2ccc(OCC)cc2O)c2ccccc2)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 1/20 0.47
CNR2 P34972 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 2/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAOB P27338 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
GAA P10253 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALOX5 P09917 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9059711 0.91 PTPN11 (0.47) ALDH1A1L3MBTL1MAOBMEN1KMT2A
SCHEMBL11551597 0.88 PTPN11 (0.51) TP53
SCHEMBL11568630 0.88 GPR88 (0.44) LMNAMAOBMEN1KMT2AHPGD
SCHEMBL11566910 0.87 MAPK1 (0.49) ALDH1A1MAPK1HPGDGAAALOX5
SCHEMBL11559419 0.86 GAA (0.46) ALDH1A1MAPK1LMNAL3MBTL1MAOB
SCHEMBL11558507 0.85 HPGD (0.50) CNR2ALDH1A1MAPK1LMNAL3MBTL1
SCHEMBL8983949 0.84 TYR (0.46) CNR2ALDH1A1LMNAMEN1KMT2A
SCHEMBL3453799 0.80 TYR (0.59) CNR2ALDH1A1L3MBTL1MEN1KMT2A
Potassium SCHEMBL9061207 0.79 TYR (0.57) CNR2ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL31413333 0.77 KMT2A (0.57) CNR2ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163746-A ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-08-07 US disclosed