Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 4/20 | 0.38 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.38 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.38 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.38 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.38 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567774 | 0.89 | ESRRA (0.54) | ESRRAFFAR1TSHRNPC1RAB9A | |
| SCHEMBL11563649 | 0.81 | ESRRA (0.49) | ESRRAFFAR1TSHRNPC1RAB9A | |
| SCHEMBL11568422 | 0.81 | POLB (0.44) | NPC1RAB9AGCGRADCY6ADCY3 | |
| SCHEMBL11567624 | 0.81 | POLB (0.44) | NPC1RAB9AGCGRADCY6ADCY3 | |
| SCHEMBL13757731 | 0.79 | KMT2A (0.50) | RAB9AGCGRADCY6ADCY3ADCY9 | |
| SCHEMBL11565999 | 0.78 | ESRRA (0.58) | ESRRAFFAR1TSHRNPC1RAB9A | |
| SCHEMBL11562974 | 0.76 | MAPT (0.56) | NPC1RAB9AGCGRADCY6ADCY3 | |
| SCHEMBL11563277 | 0.75 | PPARG (0.43) | NPC1RAB9AGCGRADCY6ADCY3 | |
| SCHEMBL11562897 | 0.75 | CYP2C19 (0.43) | FFAR1LMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL11568279 | 0.73 | POLB (0.42) | NPC1RAB9AGCGRADCY6ADCY3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |