Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 4/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563649 | 0.92 | ESRRA (0.49) | ESRRAFFAR1TSHRNPC1RAB9A | |
| SCHEMBL11568880 | 0.89 | ESRRA (0.50) | ESRRAFFAR1TSHRNPC1RAB9A | |
| SCHEMBL11561168 | 0.83 | PPARG (0.51) | F9F10PPARA | |
| SCHEMBL11564504 | 0.83 | PPARG (0.51) | F9F10PPARA | |
| SCHEMBL11565422 | 0.83 | F9 (0.46) | F9F10MEN1KMT2AMAPT | |
| SCHEMBL11565999 | 0.81 | ESRRA (0.58) | ESRRAFFAR1TSHRNPC1RAB9A | |
| SCHEMBL11568618 | 0.80 | F9 (0.48) | NPC1RAB9AF9F10MEN1 | |
| SCHEMBL11568593 | 0.79 | FFAR1 (0.46) | FFAR1F9F10MEN1KMT2A | |
| SCHEMBL11564359 | 0.78 | SLC6A2 (0.49) | ESRRALMNAF9F10MEN1 | |
| SCHEMBL11569905 | 0.77 | F9 (0.43) | F9F10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |