Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NAA50 | Q9GZZ1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035041 | 0.85 | — | — | |
| SCHEMBL7333027 | 0.84 | DPP4 (0.32) | — | |
| SCHEMBL11569073 | 0.80 | TRHR (0.39) | TRHR | |
| SCHEMBL1370285 | 0.78 | TRHR (0.52) | TRHR | |
| SCHEMBL14028666 | 0.75 | TRHR (0.61) | TRHRHDAC3HDAC1HDAC10HDAC11 | |
| SCHEMBL8256591 | 0.73 | TRHR (0.59) | TRHR | |
| SCHEMBL8611136 | 0.73 | TRHR (0.34) | TRHR | |
| SCHEMBL8781640 | 0.73 | TRHR (0.36) | TRHRHDAC3HDAC1HDAC10HDAC11 | |
| SCHEMBL10589322 | 0.72 | TRHR (0.76) | TRHR | |
| SCHEMBL7265751 | 0.72 | TRHR (0.32) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001845-A2 | Analeptic tripeptides, process for their preparation and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1979-05-16 | — | — | EP | disclosed |