Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568924 | 0.84 | TRHR (0.43) | — | |
| SCHEMBL11035041 | 0.84 | — | — | |
| SCHEMBL7333014 | 0.82 | TRHR (0.39) | — | |
| SCHEMBL7323929 | 0.81 | — | — | |
| SCHEMBL7325611 | 0.77 | — | — | |
| SCHEMBL7326055 | 0.75 | DPP4 (0.30) | DPP4DPP8DPP9 | |
| SCHEMBL7327380 | 0.75 | TRHR (0.42) | — | |
| SCHEMBL5036645 | 0.74 | TACR1 (0.40) | DPP4DPP8DPP9TACR1 | |
| SCHEMBL7326005 | 0.71 | TRHR (0.41) | — | |
| SCHEMBL10864928 | 0.71 | OPRM1 (0.43) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |